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Slit3tm1Dor
Targeted Allele Detail
Nomenclature
Symbol: Slit3tm1Dor
Name: slit homolog 3 (Drosophila); targeted mutation 1, David M Ornitz
MGI ID: MGI:2662346
Synonyms: Slit3-
Gene: Slit3  Location: Chr11:35121224-35708507 bp, + strand  Genetic Position: Chr11, 20.29 cM, cytoband A5
Congenital diaphragmatic hernia (CDH) and lung pathology in Slit3tm1Dor/Slit3tm1Dor mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83292
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slit3 Mutation:  11 strains or lines available
References
Original:  J:83292 Yuan W, et al., A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5217-22
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory