About   Help   FAQ
Ppp1r3ctm1Ars
Targeted Allele Detail
Nomenclature
Symbol: Ppp1r3ctm1Ars
Name: protein phosphatase 1, regulatory subunit 3C; targeted mutation 1, Alan R Saltiel
MGI ID: MGI:2662307
Synonyms: PTG-
Gene: Ppp1r3c  Location: Chr19:36731731-36736604 bp, - strand  Genetic Position: Chr19, 31.89 cM, cytoband C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83297
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsThe entire coding region was replaced with a neo cassette inserted by homologous recombination. Western blot analysis of adipose, liver, and muscle tissue showed reduced levels of protein in homozygous mutant mice. (J:83297)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppp1r3c Mutation:  12 strains or lines available
References
Original:  J:83297 Crosson SM, et al., PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. J Clin Invest. 2003 May;111(9):1423-32
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/15/2018
MGI 6.12
The Jackson Laboratory