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Dync1h1tm1Noh
Targeted Allele Detail
Nomenclature
Symbol: Dync1h1tm1Noh
Name: dynein cytoplasmic 1 heavy chain 1; targeted mutation 1, Nobutaka Hirokawa
MGI ID: MGI:2661091
Synonyms: cDHC-
Gene: Dync1h1  Location: Chr12:110601452-110666945 bp, + strand  Genetic Position: Chr12, 60.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78610
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details A replacement construct containing a PGK-neo cassette was inserted in the reverse orientation and replaced the second half of the first exon and the first intron of the gene. (J:78610)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dync1h1 Mutation:  13 strains or lines available
References
Original:  J:78610 Harada A, et al., Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J Cell Biol. 1998 Apr 6;141(1):51-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory