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Gdf6tm1Kng
Targeted Allele Detail
Nomenclature
Symbol: Gdf6tm1Kng
Name: growth differentiation factor 6; targeted mutation 1, David M Kingsley
MGI ID: MGI:2661063
Synonyms: Gdf6-
Gene: Gdf6  Location: Chr4:9844372-9862345 bp, + strand  Genetic Position: Chr4, 4.35 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83132
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 15 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gdf6 Mutation:  5 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: carpal/tarsal coalition, conductive deafness, scoliosis and craniosynostosis (J:83132, J:187424)

References
Original:  J:83132 Settle SH Jr, et al., Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory