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Targeted Allele Detail
Symbol: Selenoptm1Rfb
Name: selenoprotein P; targeted mutation 1, Raymond F Burk
MGI ID: MGI:2656912
Synonyms: Sepp-
Gene: Selenop  Location: Chr15:3268547-3280507 bp, + strand  Genetic Position: Chr15, 1.84 cM
Germline Transmission:  Earliest citation of germline transmission: J:82921
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsThe gene was disrupted by insertion of a neomycin resistance cassette into exon 2 via homologous recombination. The neo cassette carries stop codons in all 3 reading frames. Protein product was undetectable by Western blot and radioimmunoassay of plasma samples from homozygous mutant animals. (J:82921)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Selenop Mutation:  11 strains or lines available
Original:  J:82921 Hill KE, et al., Deletion of selenoprotein P alters distribution of selenium in the mouse. J Biol Chem. 2003 Apr 18;278(16):13640-6
All:  25 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
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