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Sgcatm1Eeng
Targeted Allele Detail
Nomenclature
Symbol: Sgcatm1Eeng
Name: sarcoglycan, alpha (dystrophin-associated glycoprotein); targeted mutation 1, Eva Engvall
MGI ID: MGI:2656910
Synonyms: ASG -
Gene: Sgca  Location: Chr11:94962791-94976327 bp, - strand  Genetic Position: Chr11, 59.01 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59165
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPortions of exons 1 and 2 and all of intron 1 were replaced with a cassette containing lacZ and neo. The absence of normal protein in homozygous mutant mice was verified by immunofluorescence and Western blot analysis. (J:59165)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sgca Mutation:  18 strains or lines available
Notes
ES cell line = SM38.
References
Original:  J:59165 Liu LA, et al., Sarcoglycan isoforms in skeletal muscle. J Biol Chem. 1999 Dec 31;274(53):38171-6
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory