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Hoxb13tm4Mrc
Targeted Allele Detail
Nomenclature
Symbol: Hoxb13tm4Mrc
Name: homeobox B13; targeted mutation 4, Mario R Capecchi
MGI ID: MGI:2656729
Synonyms: Hoxb13neo
Gene: Hoxb13  Location: Chr11:96194316-96197447 bp, + strand  Genetic Position: Chr11, 59.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82849
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 was disrupted by the insertion of a floxed neomycin selection cassette at codon 33. Hoxb13tm2Mrc was generated from this allele by in vivo cre mediated recombination. (J:82849)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb13 Mutation:  6 strains or lines available
References
Original:  J:82849 Economides KD, et al., Hoxb13 mutations cause overgrowth of caudal spinal cord and tail vertebrae. Dev Biol. 2003 Apr 15;256(2):317-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory