Rpgrip1tm1Tili
Targeted Allele Detail
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Symbol: |
Rpgrip1tm1Tili |
Name: |
retinitis pigmentosa GTPase regulator interacting protein 1; targeted mutation 1, Tiansen Li |
MGI ID: |
MGI:2655714 |
Synonyms: |
RPGRIP- |
Gene: |
Rpgrip1 Location: Chr14:52348161-52401003 bp, + strand Genetic Position: Chr14, 26.81 cM
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Alliance: |
Rpgrip1tm1Tili page
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Ultrastructural examination of Rpgrip1tm1Tili/Rpgrip1tm1Tili mouse photoreceptors
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:82755
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Modified isoform(s), Null/knockout) |
Mutation: |
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Insertion
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Mutation details: The gene was disrupted by insertion of a large cassette containing 3 duplicated exons and a neomycin resistance gene. RT-PCR and sequence analysis of mRNA from homozygous mutant animals detected a premature stop codon. Absence of gene expression in homozygous animals was confirmed by Western blot analysis.
(J:82755, J:243745)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rpgrip1 Mutation: |
70 strains or lines available
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Original: |
J:82755 Zhao Y, et al., The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3965-70 |
All: |
9 reference(s) |
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