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Tg(Ela1-TAg)19Bri
Transgene Detail
Nomenclature
Symbol: Tg(Ela1-TAg)19Bri
Name: transgene insertion 19, Ralph L Brinster
MGI ID: MGI:2655223
Synonyms: EL-TAg, line 264-4, Tg(Ela-1, SV40E + Ela-1, neo)Bri19
Transgene: Tg(Ela1-TAg)19Bri  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgenic construct contained 7.2 kb of the rat Ela1 promoter region adjoined to sequence encoding SV40 small and large T antigens. The promoter was used to drive transgenic expression in pancreatic acinar cells. (J:80845)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
The founder line contained 8 copies of the transgenic construct.
References
Original:  J:80845 Ornitz DM, et al., Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. Science. 1987 Oct 9;238(4824):188-93
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory