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Rr27tm1.1Kpfe
Targeted Allele Detail
Nomenclature
Symbol: Rr27tm1.1Kpfe
Name: regulatory region 27; targeted mutation 1.1, Karl Pfeifer
MGI ID: MGI:2655219
Synonyms: DMRDeltaG, H19tm1.1Kpfe
Gene: Rr27  Location: unknown  Genetic Position: Chr7, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82798
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe floxed 0.1 kb region containing the differentially methylated region (DMR) was excised from H19tm1Kpfe via cre mediated recombination in the germ line. (J:82798)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr27 Mutation:  2 strains or lines available
References
Original:  J:82798 Srivastava M, et al., H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19. Genes Dev. 2000 May 15;14(10):1186-95
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory