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Foxp3tm1.1Ayr
Targeted Allele Detail
Nomenclature
Symbol: Foxp3tm1.1Ayr
Name: forkhead box P3; targeted mutation 1.1, Alexander Y Rudensky
MGI ID: MGI:2654936
Synonyms: Foxp3-, Foxp3-GFP, Foxp3 KO
Gene: Foxp3  Location: ChrX:7579676-7595243 bp, + strand  Genetic Position: ChrX, 3.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82560
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA floxed fragment encompassing exons 1 through 5 was deleted via cre mediated recombination in the germline. (J:82560)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp3 Mutation:  25 strains or lines available
References
Original:  J:82560 Fontenot JD, et al., Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. 2003 Apr;4(4):330-6
All:  39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory