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Tg(Myh6-Gnaq)40Gwd
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-Gnaq)40Gwd
Name: transgene insertion 40, Gerald W Dorn II
MGI ID: MGI:2654383
Synonyms: Galphaq-40, Tg(Myh6-Gnaq)2Gwd, Tg(Myhca-Gnaq)2Gwd
Transgene: Tg(Myh6-Gnaq)40Gwd  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Gnaq)40Gwd expresses 1 gene
 
Mutation detailsA 1.46 kb mouse Gnaq cDNA sequence under regulatory control of a full length mouse Myhca promoter was used for the transgene. The mouse Myhca promoter was used to drive transgene expression in the heart. Transgenic line designated Galphaq-40 carries 40 copies of the transgene. (J:41949)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:41949 D'Angelo DD, et al., Transgenic Galphaq overexpression induces cardiac contractile failure in mice. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8121-6
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory