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Targeted Allele Detail
Symbol: Mab21l1tm1Nao
Name: mab-21-like 1; targeted mutation 1, Naoki Takahashi
MGI ID: MGI:2654257
Synonyms: Mab21l1-
Gene: Mab21l1  Location: Chr3:55689931-55692422 bp, + strand  Genetic Position: Chr3, 26.65 cM, cytoband E3-F1
Alliance: Mab21l1tm1Nao page
Germline Transmission:  Earliest citation of germline transmission: J:82312
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire gene coding region was replaced with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutants was confirmed by whole mount in situ hybridization analysis of E10.5 homozygous mutant embryos. (J:82312)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 15 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mab21l1 Mutation:  5 strains or lines available
Original:  J:82312 Yamada R, et al., Cell-autonomous involvement of Mab21l1 is essential for lens placode development. Development. 2003 May;130(9):1759-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory