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Targeted Allele Detail
Symbol: Foxh1tm1.1Hmd
Name: forkhead box H1; targeted mutation 1.1, Hiroshi Hamada
MGI ID: MGI:2654232
Synonyms: Foxh1-
Gene: Foxh1  Location: Chr15:76668225-76669948 bp, - strand  Genetic Position: Chr15, 36.24 cM
Germline Transmission:  Earliest citation of germline transmission: J:69593
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele is derived from Foxh1tm1Hmd. Mutant animals were bred to cre-expressing line Tg(ACTB-cre)13Miya to delete exon 2 and the neo cassette. Homozygous mutant embryos did not express gene transcripts as determined by Northern blot and RT-PCR analysis. (J:69593)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxh1 Mutation:  26 strains or lines available
Original:  J:69593 Yamamoto M, et al., The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev. 2001 May 15;15(10):1242-56
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory