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Dspptm1Kul
Targeted Allele Detail
Nomenclature
Symbol: Dspptm1Kul
Name: dentin sialophosphoprotein; targeted mutation 1, Ashok B Kulkarni
MGI ID: MGI:2653208
Synonyms: Dspp-
Gene: Dspp  Location: Chr5:104170712-104180127 bp, + strand  Genetic Position: Chr5, 50.59 cM
Tooth abnormalities in Dspptm1Kul/Dspptm1Kul mice

Show the 4 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84378
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dspp Mutation:  7 strains or lines available
References
Original:  J:84378 Sreenath T, et al., Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III. J Biol Chem. 2003 Jul 4;278(27):24874-80
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory