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Ndntm2Stw
Targeted Allele Detail
Nomenclature
Symbol: Ndntm2Stw
Name: necdin; targeted mutation 2, Colin L Stewart
MGI ID: MGI:2653048
Synonyms: Ndn-null
Gene: Ndn  Location: Chr7:62348277-62349928 bp, + strand  Genetic Position: Chr7, 34.36 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57890
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe floxed neo cassette was excised from Ndntm1Stw via in vivo cre mediated recombination. Sequence encoding lacZ was left in place of protein coding sequence downstream of the endogenous codon 31. (J:57890)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 50 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ndn Mutation:  2 strains or lines available
References
Original:  J:57890 Gerard M, et al., Disruption of the mouse necdin gene results in early post-natal lethality [see comments]. Nat Genet. 1999 Oct;23(2):199-202
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory