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Lpltm1Bres
Targeted Allele Detail
Nomenclature
Symbol: Lpltm1Bres
Name: lipoprotein lipase; targeted mutation 1, Jan L Breslow
MGI ID: MGI:2651805
Synonyms: L1, LPL-
Gene: Lpl  Location: Chr8:68880491-68907448 bp, + strand  Genetic Position: Chr8, 33.88 cM
Gross pathology of Lpltm1Bres/Lpltm1Bres pups at 14-16 hours after birth

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30062
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lpl Mutation:  3 strains or lines available
References
Original:  J:30062 Weinstock PH, et al., Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest. 1995 Dec;96(6):2555-68
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory