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Pelotm1Imad
Targeted Allele Detail
Summary
Symbol: Pelotm1Imad
Name: pelota mRNA surveillance and ribosome rescue factor; targeted mutation 1, Ibrahim M Adham
MGI ID: MGI:2450933
Synonyms: Pelo-
Gene: Pelo  Location: Chr13:115224891-115226694 bp, - strand  Genetic Position: Chr13, 64.61 cM
Alliance: Pelotm1Imad page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81781
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.2 kb fragment containing exons 2 and 3 was deleted by the insertion of a neomycin selection cassette. (J:81781)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pelo Mutation:  14 strains or lines available
References
Original:  J:81781 Adham IM, et al., Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression. Mol Cell Biol. 2003 Feb;23(4):1470-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory