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Tg(Prrx1-cre)1Cjt
Transgene Detail
Nomenclature
Symbol: Tg(Prrx1-cre)1Cjt
Name: transgene insertion 1, Clifford J Tabin
MGI ID: MGI:2450929
Synonyms: Prx1cre, Prx1-cre, Prx1Cre, Prx-1 Cre, Prx-cre, Tg[Prx1-cre]1Cjt
Transgene: Tg(Prrx1-cre)1Cjt  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThis transgene expresses Cre recombinase under the control of a Prrx1 derived enhancer. This transgene is expressed in the early limb bud mesenchyme and in a subset of craniofacial mesenchyme. A germline Cre recombinase activity was observed in female, but not in male, as partially penetrant trait depending on the particular gene flanked by loxP sites. (J:77872)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prrx1 (species not specified) Summary of all recombinase alleles driven by Prrx1. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 104512 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:77872 Logan M, et al., Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis. 2002 Jun;33(2):77-80
All:  399 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory