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Cx3cr1tm1Ifc
Targeted Allele Detail
Nomenclature
Symbol: Cx3cr1tm1Ifc
Name: chemokine (C-X3-C motif) receptor 1; targeted mutation 1, Israel F Charo
MGI ID: MGI:2450885
Synonyms: CX3CR1-
Gene: Cx3cr1  Location: Chr9:120048683-120068296 bp, - strand  Genetic Position: Chr9, 71.37 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82033
Parent Cell Line:  RF8 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region of the gene was replaced with a floxed neomycin resistance cassette via homologous recombination. (J:82033)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cx3cr1 Mutation:  21 strains or lines available
References
Original:  J:82033 Haskell CA, et al., Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection. J Clin Invest. 2001 Sep;108(5):679-88
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory