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Targeted Allele Detail
Symbol: Ccr8tm1Gma
Name: chemokine (C-C motif) receptor 8; targeted mutation 1, Gabriel Marquez
MGI ID: MGI:2450726
Synonyms: CCR8-
Gene: Ccr8  Location: Chr9:120092133-120094906 bp, + strand  Genetic Position: Chr9, 71.39 cM, cytoband F4
Germline Transmission:  Earliest citation of germline transmission: J:81812
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced 508 bp preceding the ATG start site and the first 658 bp of the coding sequence. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of total thymus RNA. (J:81812)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ccr8 Mutation:  8 strains or lines available
Original:  J:81812 Goya I, et al., Absence of CCR8 Does Not Impair the Response to Ovalbumin-Induced Allergic Airway Disease. J Immunol. 2003 Feb 15;170(4):2138-46
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
The Jackson Laboratory