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Mfn2tm1Dcc
Targeted Allele Detail
Nomenclature
Symbol: Mfn2tm1Dcc
Name: mitofusin 2; targeted mutation 1, David C Chan
MGI ID: MGI:2450306
Synonyms: Mfn2-
Gene: Mfn2  Location: Chr4:147873599-147904704 bp, - strand  Genetic Position: Chr4, 78.56 cM
Defective giant cell layer of Mfn2tm1Dcc/Mfn2tm1Dcc placenta

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81438
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mfn2 Mutation:  5 strains or lines available
References
Original:  J:81438 Chen H, et al., Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol. 2003 Jan 21;160(2):189-200
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory