About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Transgenic Allele Detail
Symbol: Plekha5Tg(AMH-cre)1Flor
Name: pleckstrin homology domain containing, family A member 5; transgene insertion 1, Florian Guillou
MGI ID: MGI:2450300
Synonyms: AMH-Cre, Mis-Cre
Gene: Plekha5  Location: Chr6:140424099-140594906 bp, + strand  Genetic Position: Chr6, 70.34 cM
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
Mutation detailsThe transgene consists of a human AMH promoter, a cre recombinase gene, and genomic sequences from MT1 to provide mRNA secondary structure stability. The gene trap inserted into intron 3. Northern blot analysis shows gonad-specific transgene expression in Sertoli cells of 6 day old male mice and granulosa cells of 16 day old female mice. RT-PCR confirmed normal endogenous gene expression. The insertion site of the original cre transgene was subsequenly identified as intron 3 of Plekha5. (J:81650, J:189585)
 Tissue activity of this recombinase allele
Driver: AMH     Summary of all recombinase alleles driven by AMH.

View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Plekha5 Mutation:  34 strains or lines available
Original:  J:81650 Lecureuil C, et al., Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice. Genesis. 2002 Jul;33(3):114-8
All:  50 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 5.21
The Jackson Laboratory