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Pou2f3tm1Rsd
Targeted Allele Detail
Nomenclature
Symbol: Pou2f3tm1Rsd
Name: POU domain, class 2, transcription factor 3; targeted mutation 1, Michael G Rosenfeld
MGI ID: MGI:2450109
Synonyms: Skn-1a/i-
Gene: Pou2f3  Location: Chr9:43123939-43210369 bp, - strand  Genetic Position: Chr9, 24.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42016
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced 5.0 kb of sequence encoding a part of the amino terminus, all of the POU-specific domain, and a large part of the POU homeodomain. RNase protection assay did not detect transcript in either adult or neonatal skin from homozygous mutant animals. (J:42016)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou2f3 Mutation:  6 strains or lines available
References
Original:  J:42016 Andersen B, et al., Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation. Genes Dev. 1997 Jul 15;11(14):1873-84
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory