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Sema3atm1Mcf
Targeted Allele Detail
Nomenclature
Symbol: Sema3atm1Mcf
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; targeted mutation 1, Mark C Fishman
MGI ID: MGI:2449920
Gene: Sema3a  Location: Chr5:13125414-13602565 bp, + strand  Genetic Position: Chr5, 4.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35824
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe exon containing the start codon and encoding 38 amino acids was replaced with a neomycin selection cassette inserted by homologous recombination. Northern blot analysis showed low levels of transcript in homozygous mutant mice. (J:35824)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sema3a Mutation:  26 strains or lines available
References
Original:  J:35824 Behar O, et al., Semaphorin III is needed for normal patterning and growth of nerves, bones and heart. Nature. 1996 Oct 10;383(6600):525-8
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory