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Tg(Ela1-Tgfa)150Bri
Transgene Detail
Nomenclature
Symbol: Tg(Ela1-Tgfa)150Bri
Name: transgene insertion 150, Ralph L Brinster
MGI ID: MGI:2449466
Synonyms: 2261-3, Ela-Tgfa, EL-TGFalpha-hGH Line 2261-3, Tg(Ela-1,rTgfa)Bri150
Transgene: Tg(Ela1-Tgfa)150Bri  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ela1-Tgfa)150Bri expresses 1 gene
 
Mutation detailsThis transgene contains the rat elastase (Ela1) promoter and rat transforming growth factor alpha cDNA. The vector also contains part of the human growth hormone gene (containing poly(A)). (J:28451)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Additional lines were produced: 151, 153, and 154.
References
Original:  J:28451 Sandgren EP, et al., Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell. 1990 Jun 15;61(6):1121-35
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/15/2020
MGI 6.15
The Jackson Laboratory