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Car8wdl
Spontaneous Allele Detail
Nomenclature
Symbol: Car8wdl
Name: carbonic anhydrase 8; waddles
MGI ID: MGI:2449035
Synonyms: rig, rigoletto
Gene: Car8  Location: Chr4:8143362-8239041 bp, - strand  Genetic Position: Chr4, 3.53 cM
Mutation
origin
Strain of Origin:  C57BLKS/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsMutant mice contain a 19-nucleotide deletion, 15 of which are flanked by two AAGG motifs. Car8 transcript is absent in homozygous mice, suggesting that this is a null mutation. (J:103673)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Car8 Mutation:  4 strains or lines available
Notes
This mutation arose at The Jackson Laboratory.
References
Original:  J:81344 Harris BS, et al., A new mutation, waddles (wdl), on mouse Chromosome 4. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003;
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/31/2018
MGI 6.12
The Jackson Laboratory