Ncoa6tm1.1Jkr
Targeted Allele Detail
|
Symbol: |
Ncoa6tm1.1Jkr |
Name: |
nuclear receptor coactivator 6; targeted mutation 1.1, Janardan K Reddy |
MGI ID: |
MGI:2448999 |
Synonyms: |
PRIP- |
Gene: |
Ncoa6 Location: Chr2:155232585-155315741 bp, - strand Genetic Position: Chr2, 77.26 cM, cytoband H2
|
Alliance: |
Ncoa6tm1.1Jkr page
|
|
Developmental retardation and abnormalities in Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr E12.5 mutants
Show the 4 phenotype image(s) involving this allele.
|
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:81217
|
Parent Cell Line: |
HM-1 (ES Cell)
|
Strain of Origin: |
129P2/OlaHsd-Hprt1b-m3
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutation: |
|
Intragenic deletion
|
|
|
Mutation details: Floxed exon 7 was deleted via cre-mediated homologous recombination by mating Ncoa6tm1Jkr animals to the cre deleter strain TgN(EIIa-cre)C5379Lmgd. Homozygous mutant embryos were detected by PCR genotyping up to day E13.5 but did not survive until birth.
(J:81217)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Ncoa6 Mutation: |
100 strains or lines available
|
|
Original: |
J:81217 Zhu YJ, et al., Coactivator PRIP, the Peroxisome Proliferator-activated Receptor-interacting Protein, Is a Modulator of Placental, Cardiac, Hepatic, and Embryonic Development. J Biol Chem. 2003 Jan 17;278(3):1986-90 |
All: |
1 reference(s) |
|