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Foxi1tm1Sven
Targeted Allele Detail
Nomenclature
Symbol: Foxi1tm1Sven
Name: forkhead box I1; targeted mutation 1, Sven Enerback
MGI ID: MGI:2448634
Synonyms: Fkh10-
Gene: Foxi1  Location: Chr11:34154341-34158089 bp, - strand  Genetic Position: Chr11, 19.65 cM, cytoband A5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:51291
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of the forkhead domain-encoding exon with a PGK-neo cassette via homologous recombination. (J:51291)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 18 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxi1 Mutation:  15 strains or lines available
References
Original:  J:51291 Hulander M, et al., The winged helix transcription factor Fkh10 is required for normal development of the inner ear. Nat Genet. 1998 Dec;20(4):374-6
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory