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Foxm1tm1Rhc
Targeted Allele Detail
Nomenclature
Symbol: Foxm1tm1Rhc
Name: forkhead box M1; targeted mutation 1, Robert H Costa
MGI ID: MGI:2448247
Synonyms: Foxm1b-, Foxm1b fl, Foxm1fl, Foxm1flox, FoxM1flox
Gene: Foxm1  Location: Chr6:128362967-128376146 bp, + strand  Genetic Position: Chr6, 62.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81015
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA single loxP site was introduced into intron 3 and a floxed PGK-neo cassette was introduced downstream of exon 7 through homologous recombination. (J:81015)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxm1 Mutation:  17 strains or lines available
Notes

ES cell line was not specified; strain was reported as 129SvJ.

References
Original:  J:81015 Wang X, et al., The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16881-6
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory