Ccnd3^tm1Pisc
Targeted Allele Detail

Summary

• Symbol: Ccnd3^tm1Pisc
• Name: cyclin D3; targeted mutation 1, Piotr Sicinski
• MGI ID: MGI:2448172
• Synonyms: D3^-
• Gene: Ccnd3 Location: Chr17:47815976-47910614 bp, + strand Genetic Position: Chr17, 23.37 cM
• Alliance: Ccnd3^tm1Pisc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80994
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.4 kb genomic fragment encompassing exons 1 and 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant embryo lysates. (J:88120)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccnd3 Mutation: 507 strains or lines available

References

• Original: J:80994 Ciemerych MA, et al., Development of mice expressing a single D-type cyclin. Genes Dev. 2002 Dec 15;16(24):3277-89
• All: 27 reference(s)