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Ccnd3tm1Pisc
Targeted Allele Detail
Nomenclature
Symbol: Ccnd3tm1Pisc
Name: cyclin D3; targeted mutation 1, Piotr Sicinski
MGI ID: MGI:2448172
Synonyms: D3-
Gene: Ccnd3  Location: Chr17:47505051-47599691 bp, + strand  Genetic Position: Chr17, 23.37 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80994
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.4 kb genomic fragment encompassing exons 1 and 2 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of homozygous mutant embryo lysates. (J:88120)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 30 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccnd3 Mutation:  537 strains or lines available
References
Original:  J:80994 Ciemerych MA, et al., Development of mice expressing a single D-type cyclin. Genes Dev. 2002 Dec 15;16(24):3277-89
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory