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Ccr8tm1Lira
Targeted Allele Detail
Nomenclature
Symbol: Ccr8tm1Lira
Name: chemokine (C-C motif) receptor 8; targeted mutation 1, Sergio A Lira
MGI ID: MGI:2447888
Synonyms: CCR8-
Gene: Ccr8  Location: Chr9:120092133-120094906 bp, + strand  Genetic Position: Chr9, 71.39 cM, cytoband F4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67918
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of the entire Ccr8 coding sequence with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis of lung mRNA. (J:67918)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr8 Mutation:  12 strains or lines available
References
Original:  J:67918 Chensue SW, et al., Aberrant in vivo t helper type 2 cell response and impaired eosinophil recruitment in cc chemokine receptor 8 knockout mice. J Exp Med. 2001 Mar 5;193(5):573-84
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory