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Isl2tm1Arbr
Targeted Allele Detail
Nomenclature
Symbol: Isl2tm1Arbr
Name: insulin related protein 2 (islet 2); targeted mutation 1, Sylvia Arber
MGI ID: MGI:2447837
Synonyms: Isl2DTA
Gene: Isl2  Location: Chr9:55538672-55546180 bp, + strand  Genetic Position: Chr9, 30.13 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69623
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation detailsAn IRES-loxP-stop-loxP-DTA (diphtheria toxin) cassette was inserted into the sequences encoding the 3'UTR of the gene. (J:69623)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Isl2 Mutation:  5 strains or lines available
References
Original:  J:69623 Yang X, et al., Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory