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Nrg1tm3Cbm
Targeted Allele Detail
Nomenclature
Symbol: Nrg1tm3Cbm
Name: neuregulin 1; targeted mutation 3, Carmen Birchmeier
MGI ID: MGI:2447761
Synonyms: nrg-1f, nrg-1flox
Gene: Nrg1  Location: Chr8:31818028-31918203 bp, - strand  Genetic Position: Chr8, 18.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69623
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    A floxed allele was generated that contained loxP sites inserted into intron 6 and in intron 9. (J:69623)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrg1 Mutation:  5 strains or lines available
References
Original:  J:69623 Yang X, et al., Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory