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Tg(KRT14-cre/PGR)1Der
Transgene Detail
Nomenclature
Symbol: Tg(KRT14-cre/PGR)1Der
Name: transgene insertion 1, Dennis R Roop
MGI ID: MGI:2447651
Synonyms: K14.CrePR1
Transgene: Tg(KRT14-cre/PGR)1Der  Location: unknown  
Transgene
origin
Strain of Origin:  (ICR x FVB)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    induced by RU486 (mifepristone) or ZK98.734
Mutation:    Insertion
 
Mutation detailsThis transgene expresses a Cre recombinase and human progesterone receptor gene fusion under the control of a human keratin 14 promoter. This promoter drives expression of Cre recombinase in the basal layer of the epidermis and hair follicles. (J:69320)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT14     Summary of all recombinase alleles driven by KRT14.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:69320 Berton TR, et al., Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis. 2000 Feb;26(2):160-1
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory