Kitl^Sl-1Neu
Spontaneous Allele Detail

Summary

• Symbol: Kitl^Sl-1Neu
• Name: kit ligand; steel 1 Neuherberg
• MGI ID: MGI:2447294
• Synonyms: Mgf^Sl-1Neu, Sl-1Neu
• Gene: Kitl Location: Chr10:99851492-99936278 bp, + strand Genetic Position: Chr10, 51.4 cM
• Alliance: Kitl^Sl-1Neu page

Mutation origin

• Strain of Origin: (102/El x C3H/El)F1

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Sequence analysis of mice homozygous for this allele showed an A-to-G transition in the start codon, changing it from methionine to valine (p.M1V). The loss of the start codon is predicted to result in an N-terminally truncated protein. (J:37172)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kitl Mutation: 92 strains or lines available

References

• Original: J:37172 Graw J, et al., Molecular analysis of two new Steel mutations in mice shows a transversion or an insertion. Mamm Genome. 1996 Nov;7(11):843-6
• All: 1 reference(s)