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Tg(Tagln-tTA)1Mrab
Transgene Detail
Nomenclature
Symbol: Tg(Tagln-tTA)1Mrab
Name: transgene insertion 1, Marlene Rabinovitch
MGI ID: MGI:2447082
Synonyms: SM22alpha- tTA, tTA+
Transgene: Tg(Tagln-tTA)1Mrab  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsSequence encoding a tetracycline transactivator was adjoined to the smooth muscle cell specific transgelin promoter. The promoter was reported to drive expression in the aorta, but not in the heart, lung, kidney, bladder, intestine, or stomach. (J:70031)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:70031 Ju H, et al., Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7469-74
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory