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Tg(Prnp-tTA)F959Sbp
Transgene Detail
Nomenclature
Symbol: Tg(Prnp-tTA)F959Sbp
Name: transgene insertion F959, Stanley B Prusiner
MGI ID: MGI:2445786
Synonyms: Tg(Prnp-tTA/F959), Tg(Prnp-tTA)FV
Transgene: Tg(Prnp-tTA)F959Sbp  Location: unknown  
Transgene
origin
Strain of Origin:  FVB.129S7(B6)-Prnptm1Cwe/J
Transgene
description
Transgene Type:    Transgenic (random, expressed)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
This transgene was originally microinjected into Prnptm1Cwe oocytes. Founder F973 exhibits the highest level of transgene expression, followed by founders F959 and F966.

References
Original:  J:50359 Tremblay P, et al., Doxycycline control of prion protein transgene expression modulates prion disease in mice. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12580-5
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory