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Scamp1tm1Sud
Targeted Allele Detail
Nomenclature
Symbol: Scamp1tm1Sud
Name: secretory carrier membrane protein 1; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:2445741
Gene: Scamp1  Location: Chr13:94201310-94285857 bp, - strand  Genetic Position: Chr13, 49.22 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58332
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsExons 3 and 4 were replaced with a neomycin selection cassette inserted by homologous recombination. The deleted region encoded amino acids 46 through 144. No protein was detected in homozygous mutant mice by Western blot analysis. (J:58332)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scamp1 Mutation:  13 strains or lines available
References
Original:  J:58332 Fernandez-Chacon R, et al., Analysis of SCAMP1 function in secretory vesicle exocytosis by means of gene targeting in mice. J Biol Chem. 1999 Nov 12;274(46):32551-4
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory