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Mmp14tm1Hbh
Targeted Allele Detail
Nomenclature
Symbol: Mmp14tm1Hbh
Name: matrix metallopeptidase 14 (membrane-inserted); targeted mutation 1, Henning Birkedal-Hansen
MGI ID: MGI:2445723
Synonyms: MT1-, Mt1-MMP
Gene: Mmp14  Location: Chr14:54431604-54441258 bp, + strand  Genetic Position: Chr14, 27.79 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57969
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mmp14 Mutation:  10 strains or lines available
References
Original:  J:57969 Holmbeck K, et al., MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell. 1999 Oct 1;99(1):81-92
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory