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Tg(SFTPC-rtTA)5Jaw
Transgene Detail
Nomenclature
Symbol: Tg(SFTPC-rtTA)5Jaw
Name: transgene insertion 5, Jeffrey A Whitsett
MGI ID: MGI:2445716
Synonyms: hSPC-rtTA+, SFTPC-rtTA, Sp-c-rtta, SP-CrtTA, SPC-rtTA, SP-C-rtTA mice (Line 1), SP-C-rtTAtg, SP-CrtTAtg, Tg(SFTPC-rtTA)1Jaw
Transgene: Tg(SFTPC-rtTA)5Jaw  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe transgene is composed of 3.7 kb of human SFTPC promoter, a reverse tetracycline responsive transactivator gene (rt-TA), and a 0.45 kb SV40 polyadenylation signal. Transgene expression was confirmed by RT-PCR analysis. The human SFTPC promoter is active in respiratory epithelial cells. (J:61736)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
References
Original:  J:61736 Tichelaar JW, et al., Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J Biol Chem. 2000 Apr 21;275(16):11858-64
All:  105 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory