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Cer1tm1Belo
Targeted Allele Detail
Nomenclature
Symbol: Cer1tm1Belo
Name: cerberus 1, DAN family BMP antagonist; targeted mutation 1, Jose Antonio Belo
MGI ID: MGI:2445497
Synonyms: cer-l-
Gene: Cer1  Location: Chr4:82881751-82885148 bp, - strand  Genetic Position: Chr4, 39.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62082
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3.5 kb restriction fragment containing the majority of exon 1 and all of exon 2 was replaced with a construct containing IRES-lacZ and neo. Mutant mice did not express lacZ due to a deletion of several nucleotides in the IRES. (J:62082)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cer1 Mutation:  4 strains or lines available
References
Original:  J:62082 Belo JA, et al., Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development [letter]. Genesis. 2000 Apr;26(4):265-70
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory