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Targeted Allele Detail
Symbol: Cer1tm1Belo
Name: cerberus 1, DAN family BMP antagonist; targeted mutation 1, Jose Antonio Belo
MGI ID: MGI:2445497
Synonyms: cer-l-
Gene: Cer1  Location: Chr4:82881751-82885148 bp, - strand  Genetic Position: Chr4, 39.4 cM
Germline Transmission:  Earliest citation of germline transmission: J:62082
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 3.5 kb restriction fragment containing the majority of exon 1 and all of exon 2 was replaced with a construct containing IRES-lacZ and neo. Mutant mice did not express lacZ due to a deletion of several nucleotides in the IRES. (J:62082)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 30 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cer1 Mutation:  7 strains or lines available
Original:  J:62082 Belo JA, et al., Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development [letter]. Genesis. 2000 Apr;26(4):265-70
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory