About   Help   FAQ
Med21tm1Ryng
Targeted Allele Detail
Nomenclature
Symbol: Med21tm1Ryng
Name: mediator complex subunit 21; targeted mutation 1, Richard A Young
MGI ID: MGI:2445456
Synonyms: Srb7-
Gene: Med21  Location: Chr6:146642579-146650600 bp, + strand  Genetic Position: Chr6, 77.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57760
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a selection cassette (containing either neomycin or hygromycin) through homologous recombination. (J:57760)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Med21 Mutation:  18 strains or lines available
References
Original:  J:57760 Tudor M, et al., Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. Genes Dev. 1999 Sep 15;13(18):2365-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/23/2021
MGI 6.16
The Jackson Laboratory