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Med21tm1Ryng
Targeted Allele Detail
Summary
Symbol: Med21tm1Ryng
Name: mediator complex subunit 21; targeted mutation 1, Richard A Young
MGI ID: MGI:2445456
Synonyms: Srb7-
Gene: Med21  Location: Chr6:146544077-146552098 bp, + strand  Genetic Position: Chr6, 77.7 cM
Alliance: Med21tm1Ryng page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57760
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a selection cassette (containing either neomycin or hygromycin) through homologous recombination. (J:57760)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Med21 Mutation:  18 strains or lines available
References
Original:  J:57760 Tudor M, et al., Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. Genes Dev. 1999 Sep 15;13(18):2365-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory