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St3gal3tm1Jxm
Targeted Allele Detail
Nomenclature
Symbol: St3gal3tm1Jxm
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3; targeted mutation 1, Jamey Marth
MGI ID: MGI:2445404
Synonyms: ST3Gal-IIIdelta
Gene: St3gal3  Location: Chr4:117932154-118134914 bp, - strand  Genetic Position: Chr4, 53.84 cM, cytoband D1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80119
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe exon encoding the transmembrane domain was replaced with a single loxP site after the insertion of loxP sites and subsequent expression of cre recombinase in ES cells. (J:80119)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any St3gal3 Mutation:  25 strains or lines available
References
Original:  J:80119 Ellies LG, et al., Sialyltransferase specificity in selectin ligand formation. Blood. 2002 Nov 15;100(10):3618-25
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory