About   Help   FAQ
Ccr5tm1Brv
Targeted Allele Detail
Nomenclature
Symbol: Ccr5tm1Brv
Name: chemokine (C-C motif) receptor 5; targeted mutation 1, Rodrigo Bravo
MGI ID: MGI:2429994
Synonyms: ccr5-
Gene: Ccr5  Location: Chr9:124121543-124147699 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46941
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr5 Mutation:  4 strains or lines available
Notes
ES cell line = CJ7 (129S1/Sv-p+ Tyr+ Kitl+) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+).

References
Original:  J:46941 Zhou Y, et al., Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol. 1998 Apr 15;160(8):4018-25
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory