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Pmltm1Ppp
Targeted Allele Detail
Nomenclature
Symbol: Pmltm1Ppp
Name: promyelocytic leukemia; targeted mutation 1, Pier P Pandolfi
MGI ID: MGI:2429949
Synonyms: PML-
Gene: Pml  Location: Chr9:58218076-58249786 bp, - strand  Genetic Position: Chr9, 31.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46381
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 2, which encodes the RING-finger domain, was replaced with a neomycin resistance cassette. (J:46381)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pml Mutation:  65 strains or lines available
References
Original:  J:46381 Wang ZG, et al., Role of PML in cell growth and the retinoic acid pathway. Science. 1998 Mar 6;279(5356):1547-51
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory