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Dps3C57BL/6J
QTL Variant Detail
Nomenclature
QTL variant: Dps3C57BL/6J
Name: delta power in slow-wave sleep 3; C57BL/6J
MGI ID: MGI:2429723
QTL: Dps3  Location: Chr17:33600747-35939288 bp  Genetic Position: Chr17, cM position of peak correlated region/allele: 17.98 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:68838

The authors indicated that short-wave sleep in mice can be measured by EEG activity within the 1-4 Hz range or delta power. Sleep loss results in an increase in delta power whereas excess sleep causes a decrease in delta power. The differences in delta power could be measured as a QTL in 25 strains within the BXD/Ty recombinant inbred line. QTL Dps3 was found on mouse Chromosome 17 with the closest linked markers identified as D17Mit16 , D17Mit28 and D17Mit233 with a LOD score of 3.17. The suggestive range was from 16.6 - 22.9 cM.

References
Original:  J:68838 Franken P, et al., The homeostatic regulation of sleep need is under genetic control. J Neurosci. 2001 Apr 15;21(8):2610-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory