Gt(ROSA)26Sortm1(FLP1)Dym
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(FLP1)Dym |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Susan Dymecki |
MGI ID: |
MGI:2429412 |
Synonyms: |
CAGGS-Flpe, flipper, FLP, FLP deleter, FLPe, FLPeR, R26Fki, R26FLPe, ROSA26Fki, ROSA26::FLPe knock in |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(FLP1)Dym page
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Germline Transmission: |
Earliest citation of germline transmission:
J:66893
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Parent Cell Line: |
AK7 (ES Cell)
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Strain of Origin: |
129S4/SvJaeSor
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm1(FLP1)Dym expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Gt(ROSA)26Sor (MGI:104735) |
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Mutation details: An enhanced flp cassette containing a splice acceptor site was ligated to a downstream PGK-neo cassette and inserted at the endogenous locus. Efficient frt-specific recombination in transgenic mice carrying a reporter gene was reported to reflect constituitive expression of the Gt(ROSA)26Sor from preimplantation onward.
(J:66893, J:92442)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Gt(ROSA)26Sor
(mouse)
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Original: |
J:66893 Farley FW, et al., Widespread recombinase expression using FLPeR (Flipper) mice. Genesis. 2000 Nov-Dec;28(3-4):106-10 |
All: |
793 reference(s) |
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