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Tg(Hsp70-1-cre)6Arge
Transgene Detail
Nomenclature
Symbol: Tg(Hsp70-1-cre)6Arge
Name: transgene insertion 6, Argiris Efstratiadis
MGI ID: MGI:2389573
Synonyms: Hs-cre6, Hspa1b-cre6
Transgene: Tg(Hsp70-1-cre)6Arge  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J x CBA
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsA sequence fragment from the murine Hsp70-1 locus encompassing 655 bp of the 5' flanking and noncoding sequence was adjoined to sequence encoding cre recombinase. A single integration of the transgenic construct was identified in the founder line. Graded expression of the transgenic construct (determined by a range of 0% to 100% recombination of reporter loci) was observed in non heat shock induced embryos. Additionally, heat shock induces expression. (J:60711)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hsp70-1     Summary of all recombinase alleles driven by Hsp70-1.
 

Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:60711 Dietrich P, et al., Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome. 2000 Mar;11(3):196-205
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory