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Smad2tm1Kato
Targeted Allele Detail
Nomenclature
Symbol: Smad2tm1Kato
Name: SMAD family member 2; targeted mutation 1, Mitsuyasu Kato
MGI ID: MGI:2389478
Gene: Smad2  Location: Chr18:76241580-76305731 bp, + strand  Genetic Position: Chr18, 51.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79668
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3 and 4 were replaced with a floxed neomycin selection cassette inserted by homologous recombination. (J:79668)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad2 Mutation:  34 strains or lines available
References
Original:  J:79668 Hamamoto T, et al., Compound disruption of smad2 accelerates malignant progression of intestinal tumors in apc knockout mice. Cancer Res. 2002 Oct 15;62(20):5955-61
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory